ODCs

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3 associated genes
7 signs/symptoms

PROTEIN INTERACTIONS: 1

1 associated gene
No signs/symptoms info

Mantle cell lymphoma

Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	ATM	(0.72)	RRM2B

Citations in the biomedical literature:

Mantle cell lymphoma		Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy
	Synonym(s): - LCM - MCL - Mantle zone lymphoma		Synonym(s): - Adult-onset CPEO with mitochondrial myopathy

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Inborn errors of metabolism - Rare developmental defect during embryogenesis - Rare genetic disease - Rare neurologic disease - Rare otorhinolaryngologic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: adult Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references 1 MeSH reference: D020522		External references: No OMIM references No MeSH references

Mantle cell lymphoma
	Very frequent - Hematologic / blood / lymphatic cancer - Lymphadenopathy / polyadenopathies Frequent - Anorexia - Asthenia / fatigue / weakness - Bone marrow / medullar infiltration - Splenomegaly - Weight loss / loss of appetite / break in weight curve / general health alteration
Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy
(no data available)